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Cerebrolysin is a prescription medication currently used in the treatment of Alzheimers, and vascular dementia.
Cerebrolysin is an interesting new Nootropic with a lot of reported benefits for improving cognitive ability.
Due to its neurotrophic and neuroprotective properties, the drug has caught the attention of the neuroscientific medical community.
The drug is a peptide mixture isolated from protein found in the brain of pigs.
It has shown some remarkable effects in being able to repair brain damage and promote improved communication between neurons.
The most bizarre Nootropic, made from pig brains, is surprisingly promising. Cerebrolysin’s Nootropic benefits include better memory imprinting and recall, and is a strong neuroprotectant. For this reason, the drug is frequently prescribed for Alzheimer’s patients, or other sufferers of serious degenerative memory disorders.
Cerebrolysin also has a role in the longevity of cells, and can slow the rate of apoptosis (programmed cell death). It can also be used to treat dementia, stroke symptoms, or severe brain injuries.
This drug is currently undergoing extensive trials in countries around the world and it has been picked up by some more adventurous members of the Nootropic community.
However, there are two main reasons why Cerebrolysin is not more popular: 1) it is non-vegetarian and is made from pig brains; and 2) it has to be administered via injection in order to work.
Cerebrolysin is a natural compound produced using purified porcine (pig) brain proteins through a safe and standardized enzymatic process. From a technical standpoint, Cerebrolysin is an injectable protein-based solution that contains neuropeptides.
These neuropeptides are small biologically active brain peptides that are used by the neurons to help communicate with each other. The interesting thing about these peptides is that they are also able to penetrate the blood-brain barrier and act directly upon neurons.
Although initial results are promising, and this supplement is legal in a number of countries, more research is planned to further study the potential effects and benefits of Cerebrolysin.
The main effect of this new supplement is to help fight Alzheimer’s disease.
One the unique features of this supplement, however, is that instead of trying to eliminate the symptoms or even attack the root cause and “cure” this disease, the main goal is to delay its progression.
In order to accomplish this task, there are a number of different mechanisms of action. This includes acting as both a neuroprotective and neurotrophic agent.
As a neurotrophic, Cerebrolysin actually signals specific nerve cells to survive, differentiate, or grow. These effects are exerted on the neurons of the dorsal root ganglia close to the spinal cord.
It also works by promoting neurogenesis or the production of new neurons, especially in the hippocampus area of the brain which is thought to be critical in the development of memories.
All of the information processed in your brain goes through the hippocampus and this area becomes less functional in conditions such as Alzheimer’s. By improving brain function in this important system, you may be able to increase the rate of memory formation and make it easier to recall stored memories.
There have already been a number of studies and research findings that show some very strong potential benefits for Cerebrolysin.
The first of these is that it may actually help to increase the process of neurogenesis, or the growth of new nerve cells. This is especially critical in the hippocampus, since new neurons here can help to improve the process of memory formation.
It is also thought that if the efficiency of this process is improved you will be better able to retain and recall existing memories.
Another benefit is the ability of this supplement to promote synaptic repair, also in the hippocampus region. This means that overall neurotransmission is improved and more information can be transported back and forth between different areas of the brain.
A major benefit to those suffering from Alzheimer’s disease is that Cerebrolysin seems to be able to decrease amyloid production. These amyloids are essentially plaque build-up in the brain tissues and are one of the key characteristics of Alzheimer’s disease.
The more of this build-up there is present in the brain, the more brain damage an individual is likely to have. It stands to reason that by controlling and reducing the levels of this plaque formation, the slower the disease will progress.
Cerebrolysin may also decrease the rate of programmed cell death, also known as apoptosis. Although it is still not fully understood exactly how this works, this is thought to be yet another factor in the ability of the supplement to slow the progress of Alzheimer’s disease.
This effect may also lead the potential of Cerebrolysin being able to treat other issues like senile dementia, post-operative trauma, brain contusions, concussions, ischemic strokes, and other neurodegenerative brain disorders.
Up to this point Cerebrolysin does have a good safety track record. No toxicity or safety concerns have been noted or reported. This also includes no significant drug interactions or contraindications. Of course, there are some potential side effects.
These have all been mild, transient, and actually quite rare. For the most part, side effects have been limited to headaches, dizziness, and heat sensations. Of course, they might also be related to the injection being given to rapidly rather than the supplement.
Those who have kidney problems should not take this supplement. The same thing goes for those taking anti-depressants or MAO-inhibitors. Pregnant women and nursing mothers should also avoid this drug since there is not enough evidence to determine how it might affect their children.
At the present time there is a very specific method of dosing this supplement. This includes either being delivered via an intravenous infusion or an intramuscular injection.
Generally, treatment involves using one 5 ml ampule each day for a period of five (5) consecutive days. This schedule is strictly adhered to for a period of four weeks.
This schedule is then followed by a two-month treatment free period. During this time the effects of the supplement are to be carefully observed and noted. After these two months have expired the treatment schedule may be repeated or cycled again as deemed necessary.
It should also be pointed out that such treatment should not be entered into lightly. It is strongly advised to undertake this only with the advice and assistance of a qualified medical professional.
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