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Semax is a drug produced and prescribed mostly in Russia and Ukraine for a broad range of conditions but predominantly for its purported Nootropic, neuroprotective, and neurogenic/neurorestorative properties.
James Bond continually fought the agents of communism and many times against great odds. Soviet scientists developed master drugs to improve strength and cognitive abilities in order to defeat James Bond, but it never worked.
The truth about Russian drug development is not too far off. Even after the collapse of the Soviet Union, scientists in Russia developed powerful brain enhancing drugs like Semax. Developed in the 1980s into early 90s, Semax was authorized in Russia as a treatment for brain damage, cognitive degeneration, and stroke victims.
Semax, a Peptide, has been used in few human studies, but evidence suggests it has cognitive enhancing properties as well.
Beyond improving cognition, evidence suggests Semax can also improve mood and reduce feelings of anxiety. There are a host of other benefits. Semax works by modulating receptors in the Limbic Reticular complex and for the neurotransmitters acetylcholine, dopamine, serotonin, adenosine, histamine and others. It also activates NMDA receptors for glutamate in the central and peripheral nervous system and enhances energy metabolism in your neurons.
Additionally, Semax increases synthesis of neurotrophins, proteins and biosubstrates to protect and repair neurons while also reducing inflammation. This drug exhibits highly neuroprotective properties and has been recorded to increase mRNA for Nerve Growth Factor by 500% and for Brain Derived Neurotropic Growth Factor by 800%.
The purported benefits of Semax are extensive, promising increased memory, learning, focus, reasoning, perception, energy, immune system and perhaps more exciting, better mood. Many of these benefits are derived from the fact that Semax has a psychostimulant effect, but it lacks the negative side effects that normally go hand-in-hand with CNS stimulants.
In some user experiences and reviews of Semax, it is described as lessening the perception of mental strain and allowing you to be more productive. Experience logs often state that this drug makes all of your cognitive tasks seem to flow easier, faster and with less effort.
The effective dosage of Semax is said to be 1000 times smaller than Piracetam by weight. Semax is typically sold in a 0.1% or a 1% nasal spray solution in bottles of 3 ml which contain 60 doses each.
Some Nootropic users are wary of taking Semax because it is administered as a nasal spray. While this does make it somewhat unique compared to other Nootropic powders or pills that are ingested orally or dosed sublingually, you should not avoid Semax solely for this reason.
Ultimately this just means that Semax is more effective when absorbed into your system via the nasal mucous membrane as opposed to being passed through your digestive system.
The suggested dose of Semax for cognitive enhancement purposes is two to three drops of 0.1% solution in each nostril taken twice a day. This amounts to 50 mcg of active ingredient per spray which means if you were spraying twice in each nostril you would be getting 200 mcg of Semax per dosing.
Users may actually only need one dosage of Semax per day due to the very long half-life of the drug which can range from 12-24 hours. It is recommended that you cycle this drug for 14 days on at a time and then break from using it for 14 days before starting again.
The 1% Semax drop solution should be reserved for stroke victims or more serious medical purposes and should not be used for more than 14 days in a row.